AHJ:子宫手术并不增加心脏病风险
2021-12-20 03:14 来源:吉安妇科医院
与一些早期科学研究同样,一项原先加拿大科学研究注意到中会年未婚顺利完成胎盘输卵管(于其或不于其乳腺切除术)后,心血管疾病疾病的效用不曾飙升。这些未婚冠心病的效用并不高于自然现象绝经的未婚,该原先科学研究时说。
堪萨斯城大学助理作家Karen A. Matthews及室友在一份分析报告中会写下了他们的注意到,这份分析报告原计划于本周在线发布于《加拿大脑癌学会周报》。
Matthews,堪萨斯城的一位最出色的精神病学教授和流行病学与心理学教授,在一份原先闻公报中会表示遗憾,这些结果对准备考虑胎盘输卵管的中会年未婚来时说应该是鼓舞人心的:
“科学研究结果暗示,相对于自然现象绝经后,胎盘输卵管后的冠心病效用q水平不大或许飙升,”Matthews时说。
胎盘输卵管与冠心病效用
胎盘输卵管是一种经常见的移除未婚胎盘的手术操控。有时,病人还移除乳腺,以增大膀胱癌效用。
有时或许明显需要顺利完成该操控,比如因为癌症、胎盘下垂、纤维素所发肌瘤,或因为非经常重的月经过多与醒经,但与此同时,和所有手术一所发,仍要权衡其支出与效用。
因为荷尔蒙彻底改变,在绝经前顺利完成胎盘输卵管经常加剧非经常年期提前。
一些早期科学研究暗示胎盘输卵管减低心血管疾病疾病的长期效用,而心血管疾病疾病是未婚头号杀手。而且他们推断,如果同时切除术乳腺,该效用将很高。
但是该见解确实,主要因为这些科学研究趋向于于风险评估胎盘输卵管与/或乳腺输卵管多年之后的冠心病效用,而没将她们在手术之前就或许有的效用考虑外面。
科学研究者们动手了什么
而在该项原先科学研究中会,Matthews及其室友随访了3,302位加拿大绝经前未婚11年。这些未婚参加了全国未婚科学研究(SWAN)。
科学研究伊始,当这些未婚加入到SWAN时,她们42-52岁,胎盘完整,有至少1个乳腺,且没使用孕酮麻醉药。
在随访期间,每年给她们动手风险评估。在此期间,大部分未婚达到自然现象绝经成年,一些顺利完成了胎盘输卵管于其乳腺输卵管,而一些则不于其乳腺输卵管。
顺利完成胎盘输卵管的主要因素是纤维素所发肌瘤、月经过多和慢性脊柱醒。
科学研究者在胎盘输卵管前后风险评估了组织者的冠心病效用,并将这些数据与那些自然现象绝经的未婚先前一次月经前后的效用相比。
Matthews及其室友时说,他们的科学研究是时是多民族科学研究,了顺利完成胎盘输卵管与自然现象绝经的未婚的冠心病效用q的每年预期彻底改变。
注意到了什么
该分析标示出胎盘输卵管前后与自然现象绝经前后心血管疾病效用q发生波动,在不同个体,胎盘输卵管者与自然现象绝经者波动来进行大不相同;同时,总体波动来进行标示出胎盘输卵管者心血管疾病效用不曾飙升,科学研究者们时说。并且,此具体情况在所有人种组都一所发。
并且,即使在更改或许的影响q——比如人体精确度指数(BMI)——之后,具体情况仍一所发。胎盘输卵管于其乳腺输卵管后,BMI确实难免飙升。
因素是什么
Mathews时说他们并不确定为什么他们的注意到与标示出胎盘输卵管飙升时冠心病效用的早期科学研究不同。
一个因素或许是,他们没将眼中未婚纳入科学研究,而非经常早顺利完成胎盘输卵管加剧的冠心病效用很高。
另一个因素,Matthews时说,或许是因为该科学研究回避了因为癌症而顺利完成胎盘输卵管的未婚。
SWAN由国家老年医学科学该中心、国立医护科学该中心、国立保健科学研究院、未婚肥胖症科学研究室和必需与替代医疗中会心共同发起。
2011年,《内科学档案》周报写道,来自旧金山加利福尼亚大学的科学研究者们报道,他们注意到顺利完成了胎盘输卵管于其乳腺输卵管的未婚发生膀胱癌的效用增大,并且发生其它类型癌症、脑癌或髋骨折的效用不曾飙升时。
与胎盘切除术相关的拓展学习者:
胎盘输卵管并不减少脑癌效用Lancet Oncoloy:绝经后未婚胎盘输卵管后短期必需雌孕酮不会减少眼疾乳腺癌效用非经常多的资讯请点选:有关胎盘切除术非经常多资讯原文学习者:Hysterectomy does not increase risk of cardiovascular diseasePositive findings differ from previous studies on hysterectomy, heart disease riskHing a hysterectomy with or without ovary removal in mid-life does not increase a woman's risk of cardiovascular disease compared to women who reach natural menopause, contrary to many previously reported studies, according to research published online today in the Journal of the American College of Cardiology."Middle-aged women who are considering hysterectomy should be encouraged because our results suggest that increased levels of cardiovascular risk factors are not any more likely after hysterectomy relative to after natural menopause," said Karen A. Matthews, PhD, lead author of the study and a distinguished professor of psychiatry and professor of epidemiology and psychology at the University of Pittsburgh.Hysterectomy is the surgical removal of a woman's uterus; it is sometimes accompanied by the removal of the ovaries to decrease the risk of ovarian cancer. Hysterectomy is a common surgical procedure for women, but the benefits must be weighed against potential long-term related health consequences. Cardiovascular disease is the number one killer of women and many studies he shown increased risk of cardiovascular disease to be a health risk associated with hysterectomy, especially accompanied by ovary removal. Researchers in those studies usually evaluated cardiovascular disease risk factors years after hysterectomy and/or ovary removal and did not assess individual risk factor levels pre-surgery.For this study, investigators followed 3,302 premenopausal women between the ages of 42-52 for 11 years who were enrolled in the Study of Women's Health across the Nation (SWAN). Researchers compared cardiovascular disease risk factors in women prior to and following elective hysterectomy with or without ovary removal to the risk factors prior to and following final menstrual period in women who underwent natural menopause.This is the only multiethnic study that has tracked prospective annual changes in cardiovascular disease risk factors relative to hysterectomy or natural menopause.Investigators found that several cardiovascular disease risk factor changes differed prior to and following hysterectomy, compared to changes prior to and following a natural menopause, but those changes did not suggest an increased cardiovascular disease risk following hysterectomy, independent of body mass index, which did increase after hysterectomy with removal of ovaries. These effects were similar in all ethnic groups in the study.Dr. Matthews said it is unclear why this study's findings differed from other studies exploring hysterectomy and cardiovascular risk, but likely factors include the age of participants since hysterectomy that occurs earlier in life may present more cardiovascular risk. Also, earlier studies included women who had hysterectomy for any reason, whereas the SWAN study excluded women who had hysterectomy because of cancers. "This study will prove very reassuring to women who he undergone hysterectomy," said American College of Cardiology CardioSmart Chief Medical Expert JoAnne Foody, MD, FACC. "As with anything, if a woman is concerned about her risk for heart disease she should discuss this with her health care provider."
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